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International guidelines typically recommend oral corticosteroids for short-term use as a rescue therapy in atopic dermatitis (AD) due to their potent anti-inflammatory effects. Despite their effectiveness and cost-efficiency, the extended use of these medications in moderate-to-severe AD raises significant concerns. A recently published article on JAMA Network Open (Dermatology), investigates the relationship between the long-term exposure to oral corticosteroid therapy and the associated adverse effects (AEs) among adult patients with AD, providing critical insights into how prolonged use impacts patient safety and treatment outcomes.
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