Vitamin D: The Unassuming Ally in Diabetes

Diabetes is a growing global health concern, affecting approximately 451 million people worldwide.1 In Singapore, over 400,000 people live with diabetes, and this number is projected to reach 1 million by 2050.2 Given the widespread prevalence of diabetes, understanding potential adjunctive treatment options, such as vitamin D, is crucial.


Key takeaways

  • Vitamin D appears to have a significant impact on diabetes management, both in terms of improving insulin sensitivity and promoting healing in DFUs.
  • Vitamin D supplementation should be considered as part of the treatment protocol for T2DM, particularly in patients with vitamin D deficiency.
  • High-dose vitamin D3 supplementation has shown a substantial effect in accelerating the healing of chronic DFUs.
  • Additionally, in pre-diabetic individuals with hypovitaminosis D, supplementation with high-dose vitamin D3 can improve insulin sensitivity and reduce the risk of progression to diabetes.

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