For Healthcare Professionals Only.
Introduction:
- Prevalence of Type 2 Diabetes: Type 2 diabetes is on the rise among individuals aged over 65 in the US, with an associated increased risk of dementia.
- Role of Metformin: Metformin, approved in 1995 and the preferred first-line treatment since 2006, is known to reduce complications and mortality related to diabetes. It may also decrease dementia risk through improved glucose control or other mechanisms.
- Previous Studies and Challenges: Prior studies showed mixed results regarding metformin’s impact on dementia risk. Observational studies faced challenges like confounding factors, increasing metformin use, and changes in dementia incidence.
Login to read more
